HDAC2 and neoplasm: The expression of HDAC1, 2, and 3 were studied also in 283 HL and Reed–Sternberg cells (HRSC) on tissue microarray by Adams H. et al. All the HL that was possible to analyze expressed the HDAC2 (n = 194) and HDAC3 (n = 207) isoforms in mostly 100% of HRSC and tumor-infiltrating lymphocytes.