As shown in Figure 1C, the HCV open reading frame was efficiently transcribed and translated into viral proteins during MVA-HCV ΔC6L infection, as in the case of parental MVA-HCV; as such, a viral HCV polyprotein is properly processed into mature structural (Core, E1 and E2) and nonstructural (p7-NS2-NS3-NS4-NS5) HCV proteins. The gene discussed is SOS1; the disease is infection.