In addition, Wu et al. found that overexpression of miR-34c downregulated tau expression in gastric cancer cells [20], although the researchers did not perform experiments to test cognitive function or analyze tau proteins in neural cells, the results were confusing in that the decreased tau expression associated with miR-34a and miR-34c overexpression contradicted AD pathogenesis. The gene discussed is MAPT; the disease is gastric cancer.