Several prospective studies have demonstrated that the combination of hs‐CRP and Lp‐PLA2 improves the prediction of the risk of cardiovascular diseases, including coronary artery disease and stroke.7, 11 However, the association of hs‐CRP with Lp‐PLA2 for carotid atherosclerosis is less understood. This evidence concerns the gene PLA2G7 and Stroke.