T cells expressing PD-1 or TIM-3 were virtually undetectable in peripheral blood (Figure 2E), and the numbers of TCR clones in peripheral blood were not correlated with those in pleural effusion or BALF (r = 0.00652 and –0.0498, respectively) (Figure 3B, 3C). Here, HAVCR2 is linked to Pleural effusion.