Analysis of the network revealed significant enrichment (Benjamini–Hochberg adjusted P < 0.05, hypergeometric test) in relevant pathways such as endometrial cancer signaling, adipogenesis, Wnt/β-catenin signaling, estrogen-mediated S-phase entry, P53 signaling, and PI3K/AKT signaling (Supplementary Data 7). The gene discussed is AKT1; the disease is endometrial cancer.