We choose to detect the most common NSCLC associated EGFR mutations, E746-A750 del and L858R, because they account together for 86 to 90% of total EGFR mutations (45% for E746-A750 del and 40–45% for L858R) [11, 17, 21–23]. This evidence concerns the gene EGFR and non-small cell lung carcinoma.