TLR2 and synucleinopathy: Together with previous studies [8, 34], our current findings support the idea that levels of TLR2 play an important role in promoting the neurodegenerative pathology and deficits in models of synucleinopathy, therefore, we hypothesized that if functional inhibition of TLR2 would reduce overall burden of those pathologies in the model of synucleinopathy.