CD44 and breast cancer: Ouhtit et al. [134] showed that a combination of six well-established pro-apoptotic phytochemicals (curcumin, genistein, indol-3-carbinol, c-phycocyanin, resveratrol, and quercetin) downregulated the expression of several oncostatic markers, including CD44 in MCF-7 and MDA-MB-231 breast cancer cell lines.