ING5 and neoplasm: Nucleocytosolic translocation and downregulation of ING5 were positively associated with carcinogenesis and subsequent progression of gastric cancer, colorectal cancer, and head and neck squamous carcinoma.51, 52, 53 Here, the expression of acetylated histones H3 and ING5 was closely related to neuroblastoma tumor size, suggesting that their aberrant expression impacts the tumor growth of neuroblastomas.