MAPT and Alzheimer disease: In this study, by using multimodal PET and MR neuroimaging, we sought to identify disease-related patterns of in vivo pathology of tau aggregates using [18F]AV1451 PET, amyloid-β deposition with [18F]AV45, grey matter and white matter microstructural changes with 3-T MRI, in a group of patients with CBS compared to age-matched healthy controls and a group of patients with MCI due to AD.