The G-values for CHRM2 (rs6962027) polymorphic gene were 0.17 for ADE population and 1.34 for AD population, while for the CHRM3 (rs7511970) polymorphic gene, the G-values were 1.54 for ADE population and 0.13 for AD population (Table 3). This evidence concerns the gene CHRM3 and Alzheimer disease.