In addition, the percentage (Fig. 7f), IFN-γ production (Fig. 7g, h), BACH2 SUMOylation (Supplementary Fig. 6d) or suppressive function (Supplementary Fig. 6e) of tumor-infiltrating Treg cells from Foxp3-CreSenp3f/f mice treated with or without NAC displayed no apparent difference. The gene discussed is FOXP3; the disease is neoplasm.