In the CEACAM knockdown tumors, genes reported to be involved in the epithelial to mesenchymal transition (EMT) network of melanoma cells (see Discussion below) were significantly down- or upregulated: BRAF (−1.5 fold), CDH2 (N-cadherin, −1.6 fold), FOSL1 (or Fra-1, −1.7 fold), NRAS (−1.6 fold), SNAI2 (or SLUG, +2.0 fold) and TWIST1 (−1.6 fold). The gene discussed is TWIST1; the disease is melanoma.