For the within-group comparisons (21 TNBC vs. 21 TNBC; 11 ctrl vs. 10 ctrl; 21 ER+HBR-BC vs. 21 ER+HBR-BC; 15 ctrl2 vs. 15 ctrl2), UQ-pgQ2 consistently has low FP rates, with fewer than 10 FP DEGs determined at |Log(FC)| cutoff of 1.5, and no FP DEGs determined for higher cutoffs (Table 2). This evidence concerns the gene ESR1 and breast cancer.