Our experimental model of DM was similar to type 1 DM that occurs in humans − a disease characterized by autoimmune destruction of pancreatic insulin-secreting beta cells.37 Although the benefits of physical training for treating type 1 DM in animal studies are well described in the literature,38 a recent clinical study reported the protective effect of physical exercise on the function of newly diagnosed human beta cell lines, with type 1 DM. The gene discussed is INS; the disease is diabetes mellitus.