Conversely, we consider that cases in which blood eosinophils and/or FeNO do not decrease, are “truely steroid resistance.” In this case, since there is a possibility that non‐allergic type inflammation due to innate immunity etc. may remain 9, anti‐IL‐5, which is expected to be effective for steroid‐resistant eosinophilic inflammation, is selected. Here, IL5 is linked to inflammatory response.