Multivariate ORs (adjusted for age, NYHA class, LVEF, BMI, HF underlying disease (ischaemic vs. non-ischaemic), and eGFR) were 1.46 (95% CI 1.19–1.80, p < 0.001) and 1.45 (95% CI 1.18–1.78, p < 0.001), respectively for BNP and NT-proBNP. This evidence concerns the gene NPPB and hydrops fetalis.