A previous study conducted by Zippel et al. (2012) also detected P2X receptors in AD-MSCs, but interestingly although they did not detect P2X1 receptor expression at the mRNA level, they demonstrated that use of P2X1 receptor-selective antagonist, NF279, was able to inhibit the ATP-evoked calcium response [43]. This evidence concerns the gene P2RX1 and Alzheimer disease.