Blood testing for proteins are not routinely used for oesophageal cancers or GIST, but the proteins carcinoembryonic antigen (CEA), carbohydrate antigen-19-9 (CA 19-9), and carbohydrate antigen 72-4 (CA 72-4) have been used for monitoring disease progression of CRC and gastric cancer (33). The gene discussed is CEACAM5; the disease is carcinoma of esophagus.