CDKN2B-AS1 and coronary artery disorder: It is entirely possible that all conflicting results are correct; for example, a CAD risk-SNP could increase pro-proliferative ANRIL isoforms in endothelial, macrophage or vascular smooth muscle cells to drive atherosclerosis, whereas a diabetes risk-SNP at the same position could decrease proliferative ANRIL isoforms in beta cells to limit beta cell mass.