However, although studies have found no association between CDKN2A/B T2D SNPs and transcript level of p14ARF, p15INK4B, or p16INK4A in human islets (10, 107), an age-dependent positive association was identified between distal T2D risk-SNPs (group F in Table 1) and ANRIL expression (68). Here, CDKN2B-AS1 is linked to type 2 diabetes mellitus.