Likewise, GSEAs reveal high levels of inverse correlation between the Vav2;Vav3-dependent 4T1 transcriptome and the mRNA landscape induced by the ectopic expression of the entire miR-200 cluster in mesenchymal 4TO7 breast cancer cells (which express very low amounts of both miR-200c and E-cadherin) [35] (Fig. 3d). The gene discussed is VAV3; the disease is breast cancer.