CHAT and viral infectious disease: Thus, on average, dorsolateral ChAT neurons showed lower pS6rp immune reactivity when compared to dorsomedial ChAT neurons (Fig. 5f, j, as reported previously for rats44).To further explore the relationship between the extent of DCN vGluT2 neuron silencing and the pS6rp marker of striatal ChAT interneuron activity, we examined the correlation of the fraction of hM4Di-mCherry-positive neurons in the IntP (that arise as a consequence of different efficiency of viral infection across experiments) and the pS6rp levels in the striatum.