Along those lines, endometriosis tissues have decrease expression of ten-eleven translocation genes (TET1, TET2, and TET3), which convert 5-methylcytosine to 5-hydroxymethlcytosine and play a role in changes in levels of 5-hydroxymethylcytosine marks in endometriosis tissues and blood [52]. Here, TET3 is linked to endometriosis.