Previously we had done gene expression study of an entire panel of chemokines and their receptors between low-grade astrocytoma (Diffuse Astrocytoma) and high-grade astrocytoma (GBM), followed by gene ontology analysis and comparison with other databases which highlighted IL-8 as the most frequently upregulated chemokine in GBM. This evidence concerns the gene CXCL8 and astrocytoma (excluding glioblastoma).