To investigate the exact biological role of IL-8/CXCR1/2 signalling GBM biology, first we checked the expression of IL-8, CXCR1 and CXCR2 at mRNA and protein level in U-87MG and LN-18 cell lines (Fig. 3a and b). The gene discussed is CXCR1; the disease is glioblastoma.