To understand the function of NFATc1 in HCC cells, Huh7 and PLC cells with the lowest NFATc1 expression were transfected with pcDNA3.1‐NFATc1 plasmid (NFATc1) or empty vector pcDNA3.1 plasmid for negative control (NC), and CCK‐8 assays were used to evaluate proliferation levels. This evidence concerns the gene HSPG2 and hepatocellular carcinoma.