NUP153 and infection: However, while HIV-1N57S infection was indeed largely insensitive to NUP153 depletion in HOS and HT1080 cells, HIV-1WT and HIV-1N57S were equivalently sensitive to NUP153 knockdown in HeLa cells (Figure 8A, Figure 8—figure supplement 1, Figure 9, and Figure 9—figure supplement 1).