While a few Nup/NTR depletions affected the cell-cycle profile, decreasing the proportion of cells in G2 (in particular NUP93, NUP205, and KPNB1), and decreased the overall levels of nucleoporins, most knockdowns did not affect the cell cycle, and none caused complete growth arrest, suggesting that at least at the time of infection, cell physiology was not grossly disrupted by Nup/NTR depletion, in most cases. The gene discussed is NUP93; the disease is infection.