MX2 and infection: However, unlike full-length MX2, the MX2(N91)-ARFAPTIN2 fusion did not increase infectivity of HIV-1G89V, instead it marginally reduced HIV-1G89V infection, Conversely, like authentic MX2, the MX2(N91)-ARFAPTIN2 fusion was able to rescue the HIV-1N57S CA mutant from inhibition by CsA in HT1080 cells (Figure 8—figure supplement 3A,B).