The CsA dependence of HIV-1A92E infection in HeLa cells was exaggerated by some Nup knockdowns (e.g. NUP93, NUP205, NUP54, NUP153) while other knockdowns reduced or eliminated the enhancing effects of CsA (e.g. NUP98, NUP107, NUP155) (Figure 11A). This evidence concerns the gene NUP98 and infection.