APC and Familial adenomatous polyposis: Therefore, we suggest caution before extrapolating that EBNL-2, a suspected tumor suppressor gene, could play a role such as APC germ line mutations in the occurrence of familial adenomatous polyposis (FAP) (Cetta et al., 2001)—or of other TSGs as causal responsible for inherited multitumoral syndromes—, in the occurrence of lung ADCA.