Since the amino acid sequence of feline HGF shows 97.5, 93.3, and 93.2% homology with those of canine, mouse, and human (18, 19), the second aim of this study is that to examine whether feline-derived recombinant HGF can be used for the treatment of animals with liver diseases using a mouse model of NASH. This evidence concerns the gene HGF and metabolic dysfunction-associated steatohepatitis.