The meta-analysis conducted by Huo et al. (141) identified SCL25A37 as a novel MDD risk gene, and Zhang et al. (144) have showed that a haplotype T-C consisting of rs12457810 and rs12964485 in the 5'-upstream region of NDUFV2 may be a protective factor for the development of MDD in Han Chinese (144, 145). This evidence concerns the gene NDUFV2 and major depressive disorder.