LYZ and central nervous system cancer: For this, two human malignat skin cell lines (melanoma cell line A2058 and fibroblast from normal skin of a patient with a high grade glioma CCD25sk) were incubated with AS-48 at concentrations ranging from 200.00 to 0.048 μg/mL alone and in the presence of lysozyme (4.00 mg/mL) to check their viability by the MTT assay.