KEGG pathway analysis showed that genes involved in insulin secretion, dilated cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy (ARVC), cell adhesion molecules and hypertrophic cardiomyopathy (HCM) were downregulated in MEC compared to ESC (Fig. 7B; Supplementary Table 23). This evidence concerns the gene INS and hypertrophic cardiomyopathy.