Additionally, genetic polymorphisms that abridged expression of MYT1L in the hippocampus caused enlarged ID1 and ID3 expression, reduced TCF4 (transcription factor 4) and NEUROD6 (neurogenic differentiation 6) levels and reduced gene expression involved in cancer, neurodegeneration, long-term potentiation, and synaptic transmission. The gene discussed is TCF4; the disease is cancer.