IFNG and neoplasm: The splenocytes from the long-term survivors which survived the 2° challenge were incubated with the HER2-LLC1 tumor cells to detect tumor-specific reactivity; 5 samples (63%) in the R-115 arm, and all 3 samples in the R-LM113 survivors’ group exhibited a significant IFNγ response (Fig 5F), and a tendency towards higher reactivity in the R-115-treated mice.