As a result, 11 of these genes had increased expression in plasma cells from patients with MM that significantly overlapped between EEF1A1, UBC, UBB, CALR, CXCR4, JUND, FOS, PIM2, JUN, GAPDH, and HSP90B1 and were previously reported as upregulated in the Munshi_multiple _myeloma data set (Figure 4). The gene discussed is CALR; the disease is plasma cell myeloma.