More than that, both highly expressed ANRIL and lowly expressed miR‐181b were associated with CAD population aged over 60 years old, with smoking history, with symptoms of hypertension and hyperlipidemia, with CHOL ≥ 4.34 mmol/L, TG ≥ 1.93 mmol/L and Hcy ≥ 16.8 μmol/L (all P < 0.05) (Table 2). This evidence concerns the gene CDKN2B-AS1 and hypertensive disorder.