Besides, regarding the inflammatory factors, IL‐6, IL‐8, NF‐κB, TNF‐, iNOS, ICAM‐1, VCAM‐1 and COX‐2 expressions observed within AD mice models were all beyond those within NC and sham‐operated groups (P < 0.05) (Figure 2B,C). The gene discussed is ICAM1; the disease is Alzheimer disease.