More than that, both highly expressed ANRIL and lowly expressed miR‐181b were associated with CAD population aged over 60 years old, with smoking history, with symptoms of hypertension and hyperlipidemia, with CHOL ≥ 4.34 mmol/L, TG ≥ 1.93 mmol/L and Hcy ≥ 16.8 μmol/L (all P < 0.05) (Table 2). Here, CDKN2B-AS1 is linked to hyperlipidemia.