Besides, miR‐181b expression was markedly up‐regulated within thyroid papillary carcinoma (TPC) tissues, and down‐regulating miR‐181b expression could evidently hinder TPC cells’ proliferation and promoted their apoptosis.47 This study also verified that miR‐181b, regulated by ANRIL, participated in the mechanisms underlying proliferation and apoptosis of HCAECs cells (Figures 3, 4, 5, 6). Here, CDKN2B-AS1 is linked to differentiated thyroid carcinoma.