TGFB1 and androgen insensitivity syndrome: In the subgroups of AIS, JIS, familial idiopathic scoliosis, sporadic idiopathic scoliosis, and females, the observed genotype and allele frequencies of TGFB1 (-509C/T) differed also considerably between the cases and controls (p < 0.05, χ2-test or Fisher's exact test).