KNG1 and keratoconus: Univariate linear regression analysis of the annual incidence for each indication revealed a significant increase of endothelial pathologies, that is, BK (r2=0.47, P=0.003) and FED (r2=0.55, P=0.001) and a significant decrease in corneal scar (r2=0.72, P < 0.001) and KC (r2=0.38, P=0.009).