This difference was significant for CD38-expression (GEP) in asymptomatic vs. symptomatic myeloma (n = 34, p = 0.01; Figures 2D1–D3) and symptomatic vs. relapsed myeloma in flow cytometry (n = 52, p = 0.001), however, the absolute difference was small (Figures 2E1,E2). This evidence concerns the gene CD38 and plasma cell myeloma.