AA has been reported to maintain the MMP, inhibit the elevation of VDAC, decrease the cellular production of ROS and reduce the release of cytochrome c and apoptosis-inducing factors from the mitochondria in some neurodegenerative diseases (Xiong et al., 2009; Lee et al., 2014; Nataraj et al., 2017). This evidence concerns the gene CYCS and neurodegenerative disease.