The analysis of RNA-sequencing (RNA-seq) data downloaded from the TCGA data portal revealed that (1) ARRB1 and ARRB2 messenger RNAs (mRNAs) were significantly overexpressed in ADC compared to SCC samples with a higher difference of expression observed for ARRB1 mRNA, and (2) the expression of ARRB1 mRNA appeared considerably higher in normal cells from the non-tumoural lung tissue than in the SCC tissue, explaining in part the results obtained at the protein level (Supplementary Figure 2). Here, ARRB2 is linked to AIDS dementia complex.