Li et al. [34] study showed lncRNA ROR conferred gemcitabine resistance to pancreatic cancer cells at least partly via inducing autophagy, they further came up with lncRNA ROR/miR-124/PTBP1/PKM2 axis, which might play an important role in the regulation of gemcitabine resistance in pancreatic cancer cells. The gene discussed is PTBP1; the disease is familial pancreatic carcinoma.