Long nocoding RNA: MEG3 suppresses glioma cell migration by playing a role as competing endogenous RNA (ceRNA) of miR‐19.46 As to the target genes of miR‐19 relevant to glioma cell invasion, it has been reported that RUNX3 suppresses glioma cell invasion by depressing the transcription activity of β‐catenin/TCF4 and expression of downstream factors of β‐catenin/TCF4 such as c‐MYC and AKT1,47 so miR‐19 possibly promotes glioma cell migration by direct negative regulation on RUNX3. This evidence concerns the gene AKT1 and central nervous system cancer.