CTNNB1 and hepatocellular carcinoma: Like TERT promoter mutations, CTNNB1 mutation frequency varies in HCC cases by etiological factors, with ranges from 10 to 16% in HBV-related HCC, 20 to 40% in HCV-related HCC, and 30 to 50% in alcoholic HCC (Li et al., 2011; Ahn et al., 2014; Kawai-Kitahata et al., 2016; Rebouissou et al., 2016).