The level of NKG2D expression was significantly lower in NK cells from SSc patients in comparison with healthy controls [MFI of 5.15 (4.68–6.03) in SSc patients versus 6.92 (5.95–7.27) in healthy controls; p = 0.0009] (Figure 5A). The gene discussed is KLRK1; the disease is systemic sclerosis.