ANGPTL8 and type 2 diabetes mellitus: A recent meta-analysis of all published studies on ANGPTL8 and type 2 diabetes revealed increased circulating levels of ANGPTL8 in type 2 diabetic patients (15), consistently, our data demonstrated that serum levels of ANGPTL8 were significantly increased in type 2 diabetic patients as compared with control subjects, we also found that serum levels of ANGPTL8 in type 2 diabetic patients with A2 and A3 were significantly higher than in type 2 diabetic patients with A1.