Significant differences were found in statin use, NSAID use, systolic blood pressure (SBP), diastolic blood pressure (DBP), TG, fasting plasma glucose, fasting insulin, HOMA-IR, duration of diabetes, HbA1c, eGFR and urinary ACR between the diabetic patients and the control subjects (all P < 0.05). The gene discussed is INS; the disease is diabetes mellitus.