PMP22 and Charcot-Marie-Tooth disease type 1A: We hence suggest that a phospholipid therapy constitutes a promising translatable therapeutic rationale for CMT1A disease, which may also be applicable in conjunction with other newly emerging therapeutic options, such as treatment with antisense oligonucleotides suppressing Pmp22 mRNA, which has recently been shown to improve the disease phenotype in CMT1A animal models41.