TF and glioma: Targeting the transferrin receptor underlines the therapeutic potential of specific ligand conjugations, as demonstrated with doxorubicin-loaded lipid-coated transferrin-conjugated nanoparticles that inhibit more efficient lung tumor growth compared to non-targeted nanoparticles [73] and with a dual-targeting transferrin conjugate that is able to penetrate the blood-brain barrier during glioma-targeting therapy [74].