INS and Hypoglycemia: Total glucagon delivery (microboluses) was similar in the standard and overestimated bolus cases during the postprandial period, although most of the glucagon was delivered later in the postprandial period with overestimated boluses.13 Results of these and the present study show that in response to an overestimated bolus, an AP system may in many cases be able to avoid hypoglycemia occurrence or reduce its severity by attenuating postprandial insulin delivery; however, treatment with fast-acting CHO is still necessary in some cases, even with systems that have automated glucagon delivery.