S100A8 and infection: P. aeruginosa wild-type strain also induced expression of AMP mRNA including human beta-defensin (hBD)2, S100 calcium-binding protein (S100)A7 after 6 h of infection (Figure 1(G,H)), as did S100A8, S100A9 and cathelicidin LL37 (supplementary figure 1) but not hBD3 and ribonuclease (RNase)7 mRNA expression (data not shown).